Publications

My publications are also indexed on my Google Scholar profile.

Preprints

Kook L, Pfister N (2024). “Instrumental Variable Estimation of Distributional Causal Effects.” arXiv preprint arXiv:2406.19986. doi, pdf, GitHub.

Campanella G, Kook L, Häggström I, Hothorn T, Fuchs TJ (2022). “Deep conditional transformation models for survival analysis.” arXiv preprint arXiv:2210.11366. doi, pdf.

Kook L, Götschi A, Baumann PF, Hothorn T, Sick B (2022). “Deep interpretable ensembles.” arXiv preprint arXiv:2205.12729. doi, pdf, Software.

Methodology

Kook L, Baumann PFM, Dürr O, Sick B, Rügamer D (2024). “Estimating Conditional Distributions with Neural Networks using R package deeptrafo.” Journal of Statistical Software, 111(10), 1-36. doi, pdf, Software.

Kook L, Lundborg AR (2024). “Algorithm-agnostic significance testing in supervised learning with multimodal data.” Briefings in Bioinformatics, 25(6). doi, pdf, GitHub, CRAN.

Kook L, Saengkyongam S, Lundborg AR, Hothorn T, Peters J (2024). “Model-based causal feature selection for general response types.” Journal of the American Statistical Association. doi, pdf, GitHub, Software.

Kook L, Kolb C, Schiele P, Dold D, Arpogaus M, Fritz C, Baumann PFM, Kopper P, Pielok T, Dorigatti E, Rügamer D (2024). “How Inverse Conditional Flows Can Serve as a Substitute for Distributional Regression.” UAI 2024. doi.

Rügamer D, Kolb C, Weber T, Kook L, Nagler T (2024). “Generalizing Orthogonalization for Models with Non-linearities.” ICML 2024. doi.

Siegfried S, Kook L, Hothorn T (2023). “Distribution-Free Location-Scale Regression.” The American Statistician, 1-12. doi, pdf, Software.

Marmolejo-Ramos F, Tejo M, Brabec M, Kuzilek J, Joksimovic S, Kovanovic V, González J, Kneib T, Bühlmann P, Kook L, Briseño-Sánchez G, Ospina R (2022). “Distributional regression modeling via generalized additive models for location, scale, and shape: An overview through a data set from learning analytics.” WIREs Data Mining and Knowledge Discovery, e1479. doi, pdf.

Pawel S, Kook L, Reeve K (2023). “Pitfalls and potentials in simulation studies: Questionable research practices in comparative simulation studies allow for spurious claims of superiority of any method.” Biometrical Journal. doi, pdf, Software.

Rügamer D, Kolb C, Fritz C, Pfisterer F, Kopper P, Bischl B, Shen R, Bukas C, Barros de Andrade e Sousa L, Thalmeier D, Baumann PFM, Kook L, Klein N, Müller CL (2023). “deepregression: A Flexible Neural Network Framework for Semi-Structured Deep Distributional Regression.” Journal of Statistical Software, 105(1), 1–31. doi, pdf, Software.

Herzog L, Kook L, Götschi A, Petermann K, Hänsel M, Hamann J, Wegener S, Sick B (2022). “Deep conditional transformation models for functional outcome prediction after acute ischemic stroke.” Biometrial Journal. doi, pdf, GitHub.

Kook L, Sick B, Bühlmann P (2022). “Distributional Anchor Regression.” Statistics and Computing, 32(3), 39. doi, pdf, GitHub , Software.

Kook L, Herzog L, Hothorn T, Dürr O, Sick B (2022). “Deep and Interpretable Regression Models for Ordinal Outcomes.” Pattern Recognition. doi, pdf, Software.

Kook L, Hothorn T (2021). “Regularized Transformation Models: The tramnet Package.” The R Journal. doi, pdf, Software.

Biomedicine

Baumgartner P, Kook L, Altersberger VL, Gensicke H, Ardila-Jurado E, Kägi G, Salerno A, Michel P, Gopisingh KM, Nederkoorn PJ, Scheitz JF, Nolte CH, Heldner MR, Arnold M, Cordonnier C, Schiava LD, Hametner C, Ringleb PA, Leker RR, Jubran H, Luft AR, Engelter ST, Wegener S, the Thrombolysis F (2023). “Safety and effectiveness of IV Thrombolysis in retinal artery occlusion: A multicenter retrospective cohort study.” European Stroke Journal. doi, pdf.

Herzog L, Kook L, Hamann J, Globas C, Heldner MR, Seiffge D, Antonenko K, Dobrocky T, Panos L, Kaesmacher J, Fischer U, Gralla J, Arnold M, Wiest R, Luft AR, Sick B, Wegener S (2023). “Deep Learning Versus Neurologists: Functional Outcome Prediction in LVO Stroke Patients Undergoing Mechanical Thrombectomy.” Stroke. doi, pdf.

Schmidt MT, Studer M, Kunz A, Studer S, Bonvini JM, Bueter M, Kook L, Haile SR, Pregernig A, Beck-Schimmer B, Schläpfer M (2023). “There is no evidence that carbon dioxide-enriched oxygen before apnea affects the time to arterial desaturation, but it might improve cerebral oxygenation in anesthetized obese patients: a single-blinded randomized crossover trial.” BMC Anesthesiology, 23(1), 41. doi, pdf.

Fröhlich K, Brombacher E, Fahrner M, Vogele D, Kook L, Pinter N, Bronsert P, Timme-Bronsert S, Schmidt A, Bärenfaller K, Kreutz C, Schilling O (2022). “Benchmarking of analysis strategies for data-independent acquisition proteomics using a large-scale dataset comprising inter-patient heterogeneity.” Nature Communications, 13(1), 2622. doi, pdf.

Fahrner M, Kook L, Fröhlich K, Biniossek ML, Schilling O (2021). “A Systematic Evaluation of Semispecific Peptide Search Parameter Enables Identification of Previously Undescribed N-Terminal Peptides and Conserved Proteolytic Processing in Cancer Cell Lines.” Proteomes, 9(2). doi, pdf.

Ohmer M, Tzivelekidis T, Niedenführ N, Volceanov-Hahn L, Barth S, Vier J, Börries M, Busch H, Kook L, Biniossek ML, Schilling O, Kirschnek S, Häcker G (2019). “Infection of HeLa cells with Chlamydia trachomatis inhibits protein synthesis and causes multiple changes to host cell pathways.” Cellular microbiology, 21(4), e12993. doi, pdf.

Drendel V, Heckelmann B, Schell C, Kook L, Biniossek ML, Werner M, Jilg CA, Schilling O (2018). “Proteomic distinction of renal oncocytomas and chromophobe renal cell carcinomas.” Clinical proteomics, 15(1), 25. doi, pdf.

Saporito-Magriñá CM, Musacco-Sebio RN, Andrieux G, Kook L, Orrego MT, Tuttolomondo MV, Desimone MF, Boerries M, Borner C, Repetto MG (2018). “Copper-induced cell death and the protective role of glutathione: the implication of impaired protein folding rather than oxidative stress.” Metallomics, 10(12), 1743-1754. pdf.